How to get MNI coordinates for Epilepsiae electrodes

One of the best databases for focal epilepsy research is the Epilepsiae database of over 100 annotated datasets of inpatient intracranial and scalp electrode recordings from individuals suffering from epilepsy. It is a fantastic resource. However, it is not clear how to interpret the intracranial electrode coordinates given the current state of the Epilepsiae documentation. … More How to get MNI coordinates for Epilepsiae electrodes

Linear spatial filters (e.g., ICA, PCA) cannot perfectly extract EEG/MEG sources

Linear spatial filters (LSFs) derived from techniques like independent component analysis (ICA) or principal components analysis (PCA) are extremely popular techniques for analyzing electroencephalographic (EEG) and magnetoencephalographic data. They work by exploiting the fact that different EEG/MEG signal sources (e.g., a cortical patch or the eyes) project across the scalp with different topographies. An LSF … More Linear spatial filters (e.g., ICA, PCA) cannot perfectly extract EEG/MEG sources

Einstein’s EEG

I’ve been reading through neurological atlases of the intracranial electroencephalogram to research the frequencies of oscillations that are characteristic of different brain areas in health and disease.  Today I was able to exhume from a library Epilepsy and the Functional Anatomy of the Human Brain, a 1954 book by the pioneering Wilder Penfield and Herbert … More Einstein’s EEG

Public clinical data science data sets

Looking for a clinical data science project? Here are some free data sets that might be of use (in no particular order): Human Physiological and Neuroimaging Data Cam-CAN (Cambridge Centre for Ageing Neuroscience) dataset: fMRI, MRI, MEG, and behavioral human neurodata on people of various ages (i.e., cross-sectional data) Physionet: A wide array of clinically relevant … More Public clinical data science data sets

Slides from Greg Worrell presentation on spatial and temporal prediction in epilepsy

I had the pleasure of hearing the Mayo Clinic’s Greg Worrell give a talk on epilepsy diagnostics as part of the 2016 Anne & Max Tanenbaum Symposium on the Frontiers of Science today. Below are some slides from his talk that I’m posting mostly for my own later reference (but maybe they’re useful to you … More Slides from Greg Worrell presentation on spatial and temporal prediction in epilepsy

Towards an Atlas of Human Neocortical Oscillations

The electroencephalogram (EEG) is one of the most popular measures of human brain function and is currently the most clinically utilized. The EEG primarily reflects the synaptic activity of patches of neocortical pyramidal cells (at minimum probably around the order of 25 mm2–(Baillet, Mosher, & Leahy, 2001) and its most salient feature is intermittent oscillations … More Towards an Atlas of Human Neocortical Oscillations